Anthony appeared in Two Can Play That Game (2001), You Got Served (2004), Think Like a Man (2012), Think Like a Man Too (2014), November Rule (2015) and Destined (2015). She appeared as Lakeisha Grant in the Starz original drama series Power. She hosted the American reality television series La La's Full Court Wedding and La La's Full Court Life. She was married to NBA player Carmelo Anthony from 2010 to 2021.