Reena was born to Peter Reskyuna and Jessy in 1958 at Mangalore. She has a brother, Ivan. She pursued bachelor's degree from Madras Presentation College, Perumbavoor. She is married to Issac. They have two sons, Alan and Abin.

She started her career at 14, in Chukku movie as Sheela's daughter. She started production company, V.I.C and produced movies Druvasankamam and Ente Kadha. Now she is acting in Tele films and soap operas. Currently she is acting in Aniyathi serial in Mazhavil Manorama.