He gained critical acclaim for his portrayal of the lead character in the film "The Big Chill" (1983), which helped launch his career. He went on to deliver memorable performances in numerous films, showcasing his versatility and talent. Some of his notable movies include A Fish Called Wanda (1988), for which he won an Academy Award for Best Supporting Actor, Dave (1993), In & Out (1997), and The Emperor's Club (2002).

In addition to his film work, he has also been highly regarded for his stage performances. He has appeared in numerous Broadway productions and earned a Tony Award for his role in the musical "On the Twentieth Century" (1978). His theater credits include performances in works by Shakespeare, Chekhov, and other renowned playwrights.

Throughout his career, he has demonstrated his ability to tackle a wide range of characters, from comedic roles to dramatic and even musical ones. He is known for his charisma, wit, and skillful acting, which have made him a beloved figure in the entertainment industry.