Aziz Ansari was born in Columbia, South Carolina, to Fatima, a medical office worker, and Shoukath, a gastroenterologist. His family is from Tamil Nadu, India. He graduated from NYU as a business major in 2004. He studied at the South Carolina governors school of science and mathematics. He previously attended the Bennetsville Academy which was in his home town.

Starting out in television, he later had bit parts in the films I Love You, Man (2009), Funny People (2009), and Get Him to the Greek (2010), among others, before co-starring in the comedy 30 Minutes or Less (2011).