Patton Oswalt has been headlining at comedy clubs all over the United States since 1996, as well as appearing in his own standup specials on Comedy Central and HBO. He was chosen as Entertainment Weekly's "It" comedian in 2002. He is a regular on Late Night with Conan O'Brien (1993). His other television credits include appearances on Seinfeld (1989) and NewsRadio (1995).

As a writer, Oswalt spent two seasons on MADtv (1995) and has also written for the MTV Music Video Awards. He is currently writing screenplays and has appeared in the feature films Starsky & Hutch (2004), Man on the Moon (1999) and Magnolia (1999).