Angeli began her professional theater career in 2002 when she joined the Tanghalang Pilipino Actors’ Company, resident theater company of the Cultural Center of the Philippines. Her film credits include Ang Huling Araw Ng Linggo (2006), Adela (2008), the Arte France telemovie, Esclaves de Mers (2009), and Pink Halo‐Halo (2010).

Internationally, she is most known for her roles in Filipino auteur Lav Diaz’s films. Her first Lav Diaz film, the 9 ½‐hour Kagadanan Sa Banwaan Ning Mga Engkanto (Death In The Land Of Encantos, 2007) was awarded the Special Mention Prize, Orizzonti at the 64th Venice International Film Festival.